1983, May

The Research Center of Crete (RCC) begins its operation in Heraklion, Crete comprising three institutes:

in collaboration with the University of Crete.

1984, November

The Crete University Press (CUP) is founded in Heraklion Crete, under an agreement between the Pancretan Association and the Research Center of Crete (RCC).

1985, June

Two new Institutes are founded in Crete:

1986, April

Τhe Skinakas Observatory is jointly founded by FORTH, the University of Crete and the Institute Max Planck of Extraterrestrial Physics of Germany, within the framework of the Greek - German cooperation in Science and Technology.

1987, November

Two more Institutes join RCC:

The Foundation for Research and Technology - Hellas (FORTH) is formally established, administratively independent and one of the largest research centers in the country

1991, February

The PRAXI Network (HELP-FORWARD Hellenic Project for Wider Application of R&D) is established under the auspices of the Hellenic Federation of Enterprises (SEV), the Federation of Industries of Northern Greece (FING) and the Foundation for Research and Technology - Hellas.

1993, December

The Science and Technology Park of Crete (STEP-C) is founded, in support of the diffusion of the technical knowledge (know-how) accumulated within the Academic Community and the Research Institutes.

2000, March

CPERI (based in Thessaloniki) forms a separate nucleus of the Center for Research & Technology Hellas (CERTH) in Northern Greece.

2002, January

The Biomedical Research Institute (founded in 1998), based in Ioannina, joins FORTH.

2012, April

The Biomedical Research Institute (BRI) is integrated into the Institute of Molecular Biology & Biotechnology, as Department of Biomedical Research, based in Ioannina.

2018, February

The Institute of Astrophysics (IA) is founded in Heraklion, Crete.

2019, January

The Institute of Petroleum Research (IPR) is founded in Chania, Crete.

2021, December

The Biomedical Research Institute (BRI), is re-established.

The Institute of Petroleum Research (IPR) is renamed Institute of Geoenergy (IG).

2022, September

The Greek Institute for Human Genomics is founded in Athens.

FORTH currently comprises ten (10) Research Institutes.